GOLD--Graphical Overview of Linkage Disequilibrium

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GOLD-Graphical Overview of Linkage Disequilibrium

SUMMARY We describe a software package that provides a graphical summary of linkage disequilibrium in human genetic data. It allows for the analysis of family data and is well suited to the analysis of dense genetic maps. AVAILABILITY http://www.well.ox.ac.uk/asthma/GOLD CONTACT: [email protected]

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1. Abstract 2. Introduction 3. Models and methods 3.1. Haplotype block characterization 3.2. Measure of haplotype block LD 3.3. Test statistic and power calculation 3.4. Population genetic model of haplotype block 4. Results 4.1. Haplotype block LD measure 4.2. Power of the haplotype block LD mapping 4.3. Mapping 5. Discussion 6. Appendix 6.1. Appendix A 6.2. Appendix B 6.3. Appendix C 7. Refer...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2000

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/16.2.182